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12-11-2021, 12:46 AM
Post: #1
[F4LT] Introduction to Receptor
Introduction to Receptor
Definition of receptor, Nature of receptors, Regulations of receptors, Transducer mechanism of receptors and enzyme-link
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44min of on-demand video

Description
Definition: It is defined as a macro-molecule or binding site located on cell surface or inside the effector cell that serves to recognize the signal molecule/drug and initiate the response to it, but itself has no other function, e.g. G-protein coupled receptor.

Agonist: An agent which activates a receptor to produce an effect similar to a that of the physiological signal molecule, e.g. Muscarine and Nicotine

Antagonist: an agent which prevents the action of an agonist on a receptor or the subsequent response, but does not have an effect of its own, e.g. atropine and muscarine.

Inverse agonist: an agent which activates receptors to produce an effect in the opposite direction to that of the agonist, e.g. DMCM in BDZ receptors

Partial agonist: An agent which activates a receptor to produce submaximal effect but antagonizes the action of a full agonist, e.g. opioids

Ligand: any molecule which attaches selectively to particular receptors or sites (only binding or affinity but no functional change).

https://www.udemy.com/course/introduction-to-receptor

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